Lipitor 10 mg 28 tablet

Description:

Lipitor contains atorvastatin – a synthetic lipid-lowering agent of the statin class. It is an HMG-CoA reductase inhibitor that reduces LDL cholesterol and triglycerides while increasing HDL levels.

Indications:

Primary hypercholesterolemia (types IIa and IIb)
Mixed dyslipidemia
Heterozygous familial hypercholesterolemia (in adults and children ≥10 years)
Homozygous familial hypercholesterolemia
Hypertriglyceridemia (type IV)
Primary dysbetalipoproteinemia (type III)
Prevention of cardiovascular complications in patients with CAD and risk factors

Dosage and Administration:

Adults:
Initial dose: 10-20 mg once daily
Maintenance dose: 10-80 mg once daily
Maximum dose: 80 mg/day
Children 10-17 years (with heterozygous FH):

Initial dose: 10 mg/day
Maintenance dose: 10-20 mg/day
Take at any time of day, with or without food. Monitor lipid levels regularly.

Contraindications:

Active liver disease
Unexplained persistent elevated liver enzymes
Pregnancy and lactation
Age <10 years
Hypersensitivity to atorvastatin

Precautions:

Monitor liver function before and during therapy
Caution with CYP3A4-metabolized drugs
Risk of myopathy and rhabdomyolysis
In diabetes mellitus
In hypothyroidism
With alcohol abuse
Adverse Reactions

Common (≥1%):

Headache
Insomnia
Nausea
Constipation/diarrhea
Myalgia
Arthralgia
Increased liver enzymes

Rare:

Rhabdomyolysis
Hepatitis
Allergic reactions
Peripheral neuropathy

Drug Interactions:

Use with caution with:
CYP3A4 inhibitors (macrolides, azoles, HIV protease inhibitors)
Cyclosporine
Gemfibrozil
Niacin
Colchicine
Oral contraceptives
Special Instructions
Pregnancy: contraindicated (category X)
Lactation: contraindicated
Effect on driving: none
Renal impairment: no dose adjustment
Hepatic impairment: contraindicated

Storage Conditions:

Store at temperatures not exceeding 30°C
Protect from moisture

Packaging:

Cardboard box containing 28 tablets with leaflet