the usual starting dose is 5 mg once a day with a maximum dose of 10 mg once a day. Thin, frail or elderly patients or patients with hepatic impairment can start with 2.5 mg once a day. Adjust dosage according to the needs of each patient. Treatment should continue for 7-14 days. The recommended dose for chronic stable or vasospastic angina is 5-10 mg, wit a lower dose recommended for the elderly and
patients with hepatic impairment – most patients require 10 mg for adequate effect. The recommended dose for patients with coronary artery disease is 5-10 mg once a day.
hypersensitivity to amlodipine or other substances in the composition.
Precautions:
possible symptomatic lowering of blood pressure, especially in patients with severe aortic stenosis. Progression of angina pectoris and acute myocardial infarction may develop after starting or increasing the dose of the drug, especially in patients with severe obstructive coronary artery disease. Patients with hepatic impairment: Give slowly to patients with severe hepatic impairment.
Side effects:
occurred in less than 1% of the subjects. Central and peripheral nervous system, gastrointestinal tract: constipation, diarrhea, flatulence, pancreatitis. General: allergic reaction, back pain, hot flashes, malaise, irritability. Musculoskeletal system: arthrosis, muscle spasms. Psychiatry: sexual dysfunction (male and female), insomnia, nervousness, depression. Respiratory system: shortness of breath, epistaxis. Skin: itching, rash. Possible visual impairment, conjunctivitis, eye pain, tinnitus. Dry mouth, increased sweating. Metabolic and nutritional: hyperglycemia, thirst. Hematopoiesis: leukopenia, thrombocytopenia.
Pregnancy and lactation:
the safety of amlodipine during pregnancy has not been established. amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus. It is not known that amlodipine is excreted in human milk. Therefore, it is recommended to stop breastfeeding while using the drug.
Storage:
Store at a temperature not exceeding 30C in a dry place out of the reach of children.
Packaging:
a cardboard box contains 3 blisters of 10 tablets each, paper instructions.
