Cholesterol gallstones in the gallbladder and common bile duct in patients when surgical or endoscopic treatment is not possible. Cholesterol stones of the gallbladder and common bile duct with a diameter of not more than 1.5-2 cm after extracorporeal lithotripsy or mechanical lithotripsy. Primary biliary cirrhosis (before the formation of advanced fibrosis and cirrhosis of the liver). Chronic active hepatitis with cholestatic syndrome. Acute hepatitis, cystic fibrosis of the liver, congenital atresia of the bile duct. Biliary reflux esophagitis and gastritis. Biliary dyspeptic syndrome in cholecystopathy and biliary dyskinesia. Prevention and treatment of cholestatic syndrome caused by the use of hormonal contraceptives. To normalize liver function in patients receiving therapy with cytostatics, as well as in patients with alcoholic liver damage. Liver and other organ transplantation (adjunctive treatment).