Dufaximin 550 mg 28 tablets

Dufaximin 550 mg 28 tablets

Composition:

Each tablet contains:

• Rifaximin — 550 mg.

Pharmacological properties:

Rifaximin is an antibiotic from the rifamycin group with the following properties:

1. Antimicrobial action:
   Blocks bacterial RNA polymerase, disrupting RNA synthesis in susceptible bacteria.
   Mainly effective in the intestinal lumen, with minimal absorption into systemic circulation.

2. Minimal systemic effect:
   Poorly absorbed — acts locally in the intestines, reducing the risk of systemic side effects.

3. Additional effects:
   • Reduces ammonia production in the intestines in hepatic insufficiency
   • Improves symptoms of IBS with diarrhea (IBS-D).

Indications for use:

• Hepatic encephalopathy (to reduce the risk of recurrence)
• Irritable bowel syndrome with predominant diarrhea (IBS-D)
• Traveler’s diarrhea caused by non-invasive Escherichia coli.

Method of administration and dosage:

• Adults and children over 12 years: take 1 tablet orally once daily.
• Course duration depends on the indication:

– For hepatic encephalopathy — long-term (prophylaxis)
– For IBS-D — up to 14 days
– For diarrhea — 3 days.

📌 The tablet is taken with water, regardless of meals.
📌 The dosage must be confirmed by a physician depending on the patient’s condition.