Mavilor is a selective beta1-adrenergic receptor blocker with vasodilating properties, used to lower blood pressure and treat chronic heart failure. It decreases heart rate, reduces vascular resistance, and improves cardiac function, particularly in elderly patients.
Indications for Use
Treatment of essential hypertension.
Treatment of stable mild to moderate chronic heart failure in elderly patients (≥70 years) as an add-on to standard therapies.
Dosage and Method of Administration
-Hypertension:
Adults: 5 mg once daily at the same time each day. Effect appears within 1–2 weeks, optimal after 4 weeks.
-Renal impairment and elderly: start with 2.5 mg daily.
-Hepatic impairment: contraindicated.
-Paediatric population: not recommended under 18 years of age.
-Chronic Heart Failure (CHF):
-Start with 1.25 mg once daily, titrated every 1–2 weeks based on tolerance to a max of 10 mg/day.
-Only under supervision of experienced physician.
-In case of deterioration – reduce dose or discontinue.
-Long-term treatment. Discontinuation must be gradual.
Method of administration:
For oral use. Swallow with sufficient fluid (e.g., a glass of water). Can be taken with or without food.